解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Morphologically identical phages PZA, PZE , phi 29, and phi 15 can be distinguished by the neutralization test with rabbit antisera and by host range specificity. Each member of this phage group contains 18 kb double-stranded linear DNA carrying proteins covalently attached to its 5' ends. Physical maps of their DNA c...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::A synthetic peptide with a composition derived from the DNA sequence of v-myb of AMV was used as a hapten for immunization of rabbits. Peptide-specific immunoglobulins were isolated by affinity chromatography on a peptide-Sepharose column and used for immuno-precipitation of lysates of AMV-transformed non-producer mye...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::The effects of solvent viscosity and temperature on the spin-spin relaxation rates 1/T2 of solvent water protons in metmyoglobin and methaemoglobin solutions in the temperature range of 5-50 degrees C have been studied. Solvent viscosity is altered by changing sucrose concentration from 0 to 25% by weight. The magnitu...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::The anti-F9 and anti-spermatogenic cell sera with known cytotoxic and immunofluorescent activities were produced in albino guinea pigs immunized with F9 or spermatogenic cells emulsified with Freund's complete adjuvant. Short-term administration of the globulin fractions (3 x 50 mg at 24-h intervals + 1 x FCA on the f...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::The composition and structure of endogenous proviruses present in the genome of Italian Partridge chickens were studied by the method of blot hybridization using RAV-2 [32P]DNA or LTR of RSV as hybridization probes. The genomes of 5 out of 39 chickens analyzed did not contain endogenous proviruses related to RAV-2. Di...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Supernatants from Con A-stimulated rat spleen cell cultures containing TCGF were able to increase the sensitivity of the microcytotoxicity assay. Spleen cells from mice immunized with irradiated syngeneic tumour were precultivated for 24 h in a TCGF-containing medium. The precultivated immune spleen cells, when allowe...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Cells of intraperitoneally transplanted murine leukaemias and sarcomas (L-1210, EL-4, MC-11 and SA-1), were found to be toxic for target cells usually employed for assaying NK cells (K-562, EL-4, YAC-1). The 3H-uridine-ribonuclease method used in our study, in contrast to the 51Cr assay, revealed not only cytotoxicity...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::Normal mouse sera from non-immunized individuals of different strains gave high titres of "natural" antibodies which agglutinated RBC's of different inbred lines of chickens. Normal mouse sera of A strain and its congenic lines agglutinated RBC's of all chicken lines whereas normal sera of B10 strain and its congenic ...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::The efficiency of mercurascan on prolongation of skin allograft survival was found to depend on the sex of experimental animals. Long-term treatment of the recipients by MSC in the mouse strain combination B10--B10.LP (donor X recipient, difference in non-H-2 loci) was more efficient in females than in males. The immu...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::The synthetic steroid antiandrogen cyproterone acetate (CA) was administered subcutaneously to adult male mice of the inbred strains B10, B10.D2, B10.BR and C57BL/6 either as a single dose of 1 mg or as 10 daily doses of 0.5 mg. At 48 h after a single dose of CA, the thymus and spleen weights were markedly reduced and...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::A review of laboratory rat strains with regard to interstrain differences in different enzyme systems and other proteins is presented. Allelic distribution of polymorphic systems is shown. ...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::Poly N-(2-hydroxypropyl)methacrylamide (Duxon) was studied as a substitute of blood plasma and was found to prolong significantly the survival of semiallogeneic skin grafts in mice and rats and to reduce MLC reactions of human lymphocytes. It did not inhibit the growth of lymphocytes and the growth of the fibroblast-l...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::F1 chicken hybrids of the inbred lines CC and IC were given injections of erythrocytes from CB line chickens (differing at alloantigens of the major histocompatibility system B) or IA line chickens (differing at the A blood group system alloantigens). Injected erythrocytes were labelled with 51Cr and their gradual eli...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::Three transformation-defective mutants derived from avian sarcoma viruses of subgroup C, td PR-RSV-C (Vogt), td B77 (Toyoshima) and td daPR-RSV-C (isolated in our laboratory), were injected intravenously into 12-day-old chicken embryos and intraperitoneally into newly-hatched chickens. Both Brown Leghorn chickens and ...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::The study of the interaction of "zona-free" mouse, rat and hamster eggs with human spermatozoa showed clearly the species specificity of the plasma membrane in mice and rats where sperm penetration into the cytoplasm has never been observed. On the other hand, 66.1--77.0% of hamster eggs were penetrated and 21.9-57.5%...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::Influence of fixation and so-called pretreatment procedures used in visualization of chromosome G-bands on staining capacity of isolated biopolymers in solution and on chromatin of cell nuclei was investigated. Whereas acid fixation as well as pretreatment procedures generally decreased the maximum binding capacity of...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::The effect of active and passive antibacterial immunization on transplantation immunity was investigated in rabbits. Immunization with dead bacterial vaccines prepared from E. coli, Proteus mirabilis and Pseudmonas aeruginosa had no effect on skin allograft survival, whereas immunization with vaccines prepared from st...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::Neonatal skin grafts across a weak histocompatibility barrier (MSA-incompatible) were used only for sensitization of the recipients whose responsiveness was then tested in two different assays. On the basis of 1. functional inactivation of PEC in a PEC transfer system and 2. inhibition of macrophage migration. The dif...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::Some five to six per cent of mouse PEC spontaneously form rosettes with SRBC. This weak intercellular interaction is most likely mediated by a "receptor" for SRBC located on the surface of peritoneal macrophages. Manifestation of the receptor is influenced by the genetic background and the H-2 haplotype of PEC donors;...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::Cell surface adhesiveness of lymphocytes isolated from the peripheral blood of Papio hamadryas monkeys was compared to the adhesiveness of lymphoblastoid cell lines derived by transformation of these lymphocytes with herpesvirus Papio. For the quantitative comparison of the cell surface adhesive properties, a recently...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::A1 macroglobulin was identified in rat serum by a two-dimensional quantitative immunoelectrophoresis with intermediate gel containing monovalent anti-A1M rat serum. A second serum macroglobulin A2M antigenically related to A1M was identified in turpentine-stimulated or irradiated rats. ...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::A method is described for long-term standard production of purified virus from cultures of PR-RSV-C-transformed chicken cells. The mean yields were 4.91 mg of purified virus per liter of culture medium. Cells were grown in long-term cultures for 26 weeks. A combination of polyethylene glycol 6 000 precipitation and zo...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::Some aspects of the cell biology of normal and leukaemic haematopoietic cells are reviewed. Important points are: (a) normal and possibly also leukaemic stem cells differ from more mature cells in the kinetics as well as in cell surface antigens and other properties; (b) leukaemic cells are subject to a population siz...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::Activation of mouse lymphocytes with Con A in the presence or absence of serum in the culture medium and the effect of two polymers, PVP and CS, on this stimulation was investigated. The presence of different sera in the culture medium resulted in a different degree of lymphocyte activation and the tested polymers aff...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract::A new simple and rapid in vitro test is proposed for identification of adherent and non-adherent leucocyte subpopulations. The test based on adherence of latex (polystyrene) particles to the cell surface utilizes latex particle suspension commercially available for routine examination of the rheumatoid factor in blood...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract::Immunoprecipitation studies showed that the supernatants from the 4-hour mixed cultures of allogeneic mouse lymphoid cells contained a specific component with the alpha2-globulin electrophoretic mobility which can correspond to, or to which a "lymph node activating factor" can be bound. In addition, during allogeneic ...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract::The aerobic uptake and metabolism of D-fructose in the rings of the small intestine of conventional and germ-free piglets during development was studied. No accumulation of fructose in the intracellular water against its concentration gradient was found. In both groups of animals the intracellular concentration of fru...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract::The comparisons of immune responses to tumour allografts in male and female mice showed the following intersex differences: 1. Production of humoral antibodies is, in general, higher in females; since, however, the time course of titres differs for haemagglutinating and cytotoxic antibodies as well as with the sex, th...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::Repair DNA synthesis was examined in bone marrow cells exposed to LD 50/30 in vivo. Intensive repair synthesis took place during the irradiation, and the increase in 3HTdR uptake prevailed over the inhibitory effect of radiation and AET upon DNA synthesis. After LD 50/30, the intensity of DNA repair was reduced. Appli...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::We have followed the possible influence of H-2 system on the differences in the relative weights of testes, vesicular gland and thymus in animals of a segregating (B10 X AKR) F2 generation. H-2b/H-2b male mice had significantly higher values of relative vesicular gland weight and significantly lower values of relative...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::A specific antiandrogenic steroid cyproterone acetate was administered daily to mice of three different inbred strains starting from the day of birth until the age of 30 days. The total dose per mouse was 17.2 mg. This treatment resulted in developmental retardation which was manifested in a number of ways: at the age...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract::The effect upon the stem cells in mouse bone marrow of continuous irradiation at different daily exposure rates ranging from 1R--1,000R was investigated by means of the exogenous spleen colony assay. At exposure rates between 1 and 50R/day, a stabilized state in the CFU value becomes established, its level decreasing ...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00